No animal shakes the human consciousness quite like a bear, and few compare to the giant short-faced bears that stalked North America during the Pleistocene. Even among the mammoths and saber-toothed cats, they were a staggering sight: on all fours, the biggest would stare a six-foot person in the face and weigh close to a ton. On hind legs they towered more than ten feet, with jaws powerful enough to crush skulls and snap bones like twigs. The bears weren't invincible, however. Despite their size, they were swept off the planet in a mysterious wave of Ice Age extinctions more than ten thousand years ago, then mostly forgotten. Chasing the Ghost Bear is Mike Stark's journey into the bear's enigmatic story-its life, disappearance, and rediscovery-and those trying to piece it together today. An engaging guide through his intrepid search, Stark's story leads us from the La Brea Tar Pits in Los Angeles to a cornfield in Indiana, the far ends of the Arctic, the plains of Texas, and the swamps of Florida. Part natural history, part travelogue, and part meditation on extinction and loss, Chasing the Ghost Bear returns these magnificent beasts to their rightful place in our understanding of the world just an epoch past.

The Derelict Light takes place in Prohibition-era Astoria, Oregon, a bleak and rain-soaked fishing town where violence and vice have found a home at the edge of the continent. After the Great War the city is awash in strife: civic leaders stoking economic ambitions, Finnish socialists gunning for a revolution, gamblers and boozers operating outside the law, and salmon fishermen just trying to survive the most dangerous river on the West Coast. Then comes the Ku Klux Klan in search of fresh recruits. When a fire destroys most of the city, and a body is found hanging from the docks, the city tears at its seams. Lines are drawn, and influence wields violence. Inspired by historical events, The Derelict Light explores a Pacific Northwest town in the grips of catastrophe, caught in a bitter struggle between progress, greed, and human frailty.

Focusing on "Saccharomyces cerevisiae," the second edition of Yeast Gene Analysis represents a major reworking of the original edition, with many completely new chapters and major revisions to all previous chapters. Originally published shortly after completion of the yeast genome sequence, the new edition covers many of the major genome-wide strategies that have been developed since then such as microarray analysis of transcription, synthetic gene array studies, protein microarrays and chemical genetic approaches. It represents a valuable resource for any research laboratory using budding yeast as their experimental system in which to identify new yeast gene functions. The chapters are written in a readable style with useful background information, technical tips and specific experimental protocols included as appropriate, enabling both the novice and the experienced yeast researcher to adopt new procedures with confidence.
New chapters on:
* strain construction
* genome-wide two-hybrid approaches
* use of microarrays for transcript analysis
* real-time analysis of chromosome behaviour and FRET
* synthetic gene array technology and protein arrays
* chemical genomics and yeast prions
* RNA gene analysis and mitochondrial gene function analysis
* phylogenetic footprinting
* discovering human gene function and predicting yeast gene function

Written by Tom 'Jack' Sullivan Green, AB of Bristol in the 1920s, "Escape to the Sea" is an inspiring, first-hand account of survival against the odds of an orphan boy in early Victorian England. Recounted in a fluent style and peppered with dialogue, this gripping tale of a seaman's life chronicles both tragedy and comedy amongst the everyday lot of a working world unimaginable in the modern era. Tom traces his early life when cholera claimed his Irish immigrant parents in the London slums of 1848; being apprenticed to a tailor before running away to sea to escape a 'miserable life'. His new life as an Ordinary Seaman began at Rochester on a West Hartlepool-based ship, but when a new and tyrannical skipper made terrifying death threats he was again forced to run away.Walking from London to Liverpool in 1866 to try his hand on trans-Atlantic passages, he gives a chilling account of the last public hanging at Stafford of a murderer, William Collier. Later in the same year, Tom's travels take him to Georgia, USA where he gives an eye-witness account of the tragic plight of slaves who were freed after the American Civil War. Homeless and weakened by starvation and disease, they came to the river bank to collect driftwood only to be grabbed by alligators. This description and other harrowing sights he saw ashore leave a searing impression of the aftermath of a devastating conflict. Following various brushes with authority, Tom changes his name to Jack Green and lies low taking shore jobs near Cardiff where he turns down working digging the Severn Tunnel due to claustrophobia. Eventually settling and marrying near Bristol, he experienced more exotic times as a mariner before he 'swallowed the anchor'.These included plying the former slave routes to West Africa; accompanying the third mate of his ship with some locally-recruited native sailors to collect the future bride of a chieftain which incurred a series of adventures, some at gunpoint. "Escape to the Sea" is complemented with documents such as the author's discharge certificates, illustrations of vessels and harbours visited, maps and photographs including his handwritten will, which required that 'when the breath is out of my body' it should be buried 'with no ceremony whatsoever'. A modest end for a colourful character whose wish was that his experiences should be made available to a wider audience than his immediate family. This action-packed maritime autobiography will be of especial interest to anyone with an interest in maritime history, ships and shipping and anyone looking for a good read.

Reliable Object-Oriented Software presents the underlying principles associated with object-orientation and its practical application. More than just another text on methodology, this 1998 book focuses on the fundamental concepts related to the process of software development and architectural design in order to lay the basis necessary for the development of robust, maintainable, and evolvable software. The authors present both formal concepts and practical applications. It includes proven problem-solving techniques designed to develop readers' engineering judgement and to focus their attention on the principles of good software design and its successful application. In addition, an extensive bibliography has been compiled to guide the reader in further studies and to crystallize what is commonly accepted in the field and what is still controversial.